GI Endoscopy · 3 min read

How to Place a Capsule Endoscope During EGD Using the AdvanCE System

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by Joel Joseph , MD and Klaus Klaus Mönkemüller, MD, PhD, FASGE, FJGES

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by Joel Joseph , MD and Klaus Klaus Mönkemüller, MD, PhD, FASGE, FJGES

Department of Gastroenterology, Carilion Roanoke Memorial Hospital,                           Virginia Tech Carilion School of Medicine, Roanoke, USA

An elderly lady with obscure occult gastrointestinal bleeding could not swallow a capsule endoscope (CE) (PillCam) (Figure 1A). Therefore, an EGD was scheduled to introduce the capsule endoscope into the duodenum.

 
Figure 1

We utilized the AdvanCE capsule endoscope delivery device (Figure 1) (also see figure 3 at the end of article, which are the visual/photographic instructions from the device package).

The key steps to deploy a CE using this device are:

1. Know your equipment. The capsule deployment device consists of two parts: a) the capsule holder which contains the capsule endoscope and has a screw-receiver at its base (Figure 1A, yellow arrow), and b) the delivery catheter which has a screw on its tip (Figure 1B, light blue arrow).

2. It is important to first advance the screw catheter through the working channel of the scope (Figure 1C).

3. Once the screw catheter has exited the scope, the capsule holder (with the activated capsule) should be screwed (attached) to the screw catheter (Figure 1D). Careful attention must be paid not to lose the capsule while gently screwing the catheter to the base of the CE holder.

4. The attached capsule holder and CE should be pulled towards the scope tip (1E).

5. Introduction of the scope and CE holder into the mouth is done under direct endoscopic view. We leave a distance of about 1 to 1.5 cm between scope tip and CE, in order to facilitate visualization of the oropharynx, larynx and upper esophageal sphincter (UES).

6. Once the vocal cords are seen endoscopically, the CE will be right at the entrance of the UES. While gently turning the scope to the right (clockwise) also push the scope forward. This combined maneuver will allow for the capsule endoscope to enter the esophagus (Figure 1F).

7. The scope and CE are then advanced towards the pylorus and into the duodenum (Figure 1G). The white color (green arrow) indicates that the CE is still attached.

8. We prefer to enter the second duodenum and deliver the capsule endoscope there. Why? Because delivery of the CE in the stomach may result in delayed entry into the duodenum. Furthermore, leaving in the duodenal bulb of a patient with a “floppy” pylorus may result in capsule endoscope bouncing back into the stomach. However, if a patient has duodenal diverticulum or a tight or short genu between bulb and duodenum, we do not force placement into the second duodenum.

9. We like to apply a little water before deployment. This will stimulate duodenal motility, remove any debris from the capsule endoscope, and slightly push the capsule away once it is freed from the device.

10. Liberating or deploying the capsule endoscope is quite easy. Just ask the assistant to open the “snare” handle (Figure 2, below). This maneuver pushes the capsule away. A sign that the capsule is released is the “transparency” of the delivery device (Figure 1H). Compare to the white color present when the capsule is still attached (Figures 1F and 1G, green arrow).

 Clinical endoscopic image

Figure 2

What if the capsule was mistakenly deployed inside the stomach? No problem. A trick we use is to grab the CE with a tripod or a snare or a Roth’s net. Once grabbed, the CE is then advanced towards the pylorus and into the duodenal bulb. In these scenarios we do not purse delivery of the CE into the second duodenum, as it is harder to pass towards the second duodenum with snare, Roth net or tripod grasper.

 

Clinical endoscopic image

Figure 3

No COI by JJ or KM with any of the companies/utensils or products mentioned in this article. 

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About the authors

Joel Joseph

Joel Joseph, MD

Gastroenterologist

Lexington Medical Center, West Columbia, South Carolina, USA

Joel Joseph, MD, is a board-certified gastroenterologist practicing in West Columbia, South Carolina, and affiliated with Lexington Medical Center. He earned his medical degree from the Medical College of Georgia at Augusta University in 2018 and completed his gastroenterology fellowship at Carilion Clinic / Virginia Tech Carilion School of Medicine in 2025.

More articles by Joel →

Klaus Mönkemüller

Klaus Mönkemüller, MD, PhD, FASGE, FJGES, FESGE

Editor-in-Chief, The Practicing Endoscopist

Professor of Medicine, Carilion Memorial Hospital / Virginia Tech Carilion School of Medicine, Roanoke, Virginia, USA

Klaus Mönkemüller, MD, PhD, FASGE, FJGES, FESGE, is the editor-in-chief of The Practicing Endoscopist and the founder of EndoCollab. He is Professor of Medicine at Virginia Tech Carilion School of Medicine and a practicing endoscopist at Carilion Memorial Hospital in Roanoke, Virginia.

Dr. Mönkemüller has published extensively on endoscopic techniques and devices, with a particular focus on therapeutic endoscopy, foreign body removal, GI bleeding, and the use of caps and accessories in everyday practice. He lectures internationally and has contributed to multiple GI endoscopy textbooks and atlases.

More articles by Klaus →

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