GI Endoscopy · 1 min read

Emesis or Prolapse Gastropathy

Figure 1. Prolapse gastropathy. Upper panels show the patchy area of prolapsed stomach fundus mucosa with erythema, edema and congestion (yellow circle, arrow shows scope). The proposed mechanism of formation of prolapse gastropathy is shown in the lower graphics (C, D) (graphics source: Byfield F et al. GIE 1998).

A 35-year-old man presented with nausea and vomiting followed by hematemesis. During EGD prolapse gastropathy was diagnosed (Figure 1).

Figure 1. Prolapse gastropathy. Upper panels show the patchy area of prolapsed stomach fundus mucosa with erythema, edema and congestion (yellow circle, arrow shows scope). The proposed mechanism of formation of prolapse gastropathy is shown in the lower graphics (C, D) (graphics source: Byfield F et al. GIE 1998).

Prolapse or emesis gastropathy is an underrecognized cause of hematemesis (1, 2). This condition was initially described in the late 70s (1). Retching and vomiting results in prolapse of the lesser curvature of the stomach fundus into the esophagus (1-3). Temporary “prolapse with strangulation” results in submucosal edema, congestion and hemorrhages. Some experts also call this condition “mechanical gastritis of the cardia (3). We believe that prolapse gastropathy is a precursor of Mallory-Weiss tears and even Boerhaave’s syndrome. Therapy is aimed at relieving the underlying causes of nausea and vomiting. 

References:

  1. Retrograde gastric mucosal prolapse as a cause of haematemesis. Young GP, Thomas RJ, Wall AJ. Med J Aust. 1976;2:488–489. 

  2. Hematemesis due to prolapse gastropathy: an emetogenic injury. Byfield F, Ligresti R, Green PHR, Finegold J, Garcia-Carrasquillo RJ. Gastrointest Endosc. 1998;45:527–529. 

  3. Mechanical gastritis involving the cardia: the trauma of retching and vomiting. Chen YL. J Clin Gastroenterol. 1990;12:63–66.

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About the author

Klaus Mönkemüller

Klaus Mönkemüller, MD, PhD, FASGE, FJGES, FESGE

Editor-in-Chief, The Practicing Endoscopist

Professor of Medicine, Carilion Memorial Hospital / Virginia Tech Carilion School of Medicine, Roanoke, Virginia, USA

Klaus Mönkemüller, MD, PhD, FASGE, FJGES, FESGE, is the editor-in-chief of The Practicing Endoscopist and the founder of EndoCollab. He is Professor of Medicine at Virginia Tech Carilion School of Medicine and a practicing endoscopist at Carilion Memorial Hospital in Roanoke, Virginia.

Dr. Mönkemüller has published extensively on endoscopic techniques and devices, with a particular focus on therapeutic endoscopy, foreign body removal, GI bleeding, and the use of caps and accessories in everyday practice. He lectures internationally and has contributed to multiple GI endoscopy textbooks and atlases.

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