GI Endoscopy · 3 min read

OTSC for Duodenal Ulcer Bleeding: A One-Stop Solution for Challenging Cases

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OTSC for Duodenal Ulcer Bleeding: A One-Stop Solution for Challenging Cases

When faced with active duodenal ulcer bleeding, particularly in anatomically challenging locations, the Over-The-Scope Clip (OTSC) can be your best friend. Today I want to share a case that perfectly demonstrates why this tool should be in every endoscopist's arsenal for high-risk bleeding scenarios.

The Clinical Challenge

This patient presented with active bleeding from a duodenal ulcer located at the junction between the bulb and second portion of the duodenum. After requiring four units of packed red blood cells, urgent endoscopic intervention was needed. The ulcer showed a large visible vessel, making it an ideal candidate for OTSC placement.

The anatomical location presented several challenges. Entry into the duodenal bulb was difficult, and maintaining stable scope position was challenging due to the patient's short bulb anatomy. However, these very challenges made the case perfect for demonstrating the advantages of cap-assisted OTSC placement.

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Identifying the Bleeding Source

A key technique I always use is flushing distally to confirm the bleeding source. When we flushed toward the second portion of the duodenum, no blood appeared, confirming that the bleeding originated proximally at the bulb-D2 junction. This simple maneuver helps localize the exact bleeding site before committing to therapy.

Lecture screenshot

The bleeding was clearly coming from the left side of the lumen, while the duodenal lumen remained wide and open on the right side. This anatomy was crucial for our approach, as it meant minimal risk of luminal obstruction after clip placement.

The OTSC Advantage: Direct Approach

One of the major advantages of OTSC over traditional clipping is the simplified approach. Unlike standard clips that require grasping devices and multiple steps, the OTSC allows you to go directly onto the ulcer, suction the tissue, and release the clip. It's essentially like performing band ligation but for hemostasis.

Lecture screenshot

The transparent cap provides several key benefits:

  • Focused cleansing of the ulcer
  • Effective clot removal
  • Ability to push folds aside for better visualization
  • End-face approach to the bleeding vessel
  • Pressure hemostasis capability before clip release

Technical Execution

The cap-assisted method allows for precise targeting. You can see the security mechanism inside the cap that ensures proper attachment to the endoscope. This visual confirmation is critical for safe deployment.

Lecture screenshot

Before final deployment, I always perform one or two trial suctions to ensure we're capturing the vessel with appropriate surrounding tissue, not excessive normal mucosa. This technique ensures optimal clip placement and tissue incorporation.

Confirming Success

After clip release, immediate flushing helps clear residual clots and allows assessment of the result. Crucially, we must always check that the duodenal lumen remains patent. In this case, the right side of the lumen remained widely open, confirming no obstruction.

[SCREENSHOT 5]

Complete hemostasis was achieved with no further bleeding, demonstrating the effectiveness of this "one-stop shop" approach for this challenging anatomical location.

Key Clinical Pearls

1. OTSC excels in difficult anatomical locations where traditional tools may struggle, particularly posterior duodenal ulcers and bulb-D2 junction bleeding.

2. The cap provides multiple advantages: focused approach, clot removal, fold retraction, and the ability to apply pressure hemostasis before clip deployment.

3. Always flush distally first to confirm bleeding source location before committing to therapy.

4. Trial suction before deployment ensures optimal tissue capture without excessive normal mucosa incorporation.

5. Post-deployment luminal assessment is mandatory to confirm no obstruction, especially in the duodenum where stenosis can have serious consequences.

Closing Thoughts

The OTSC represents an efficient first or second-line therapy for challenging duodenal ulcer bleeding. Its ease of placement, effectiveness in difficult locations, and ability to provide immediate hemostasis make it an invaluable tool. The cap-assisted approach transforms what could be a technically demanding procedure into a straightforward, fast intervention.

For the complete demonstration of this technique and to see the step-by-step approach in action, watch the full video below.

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